What is SMA disease, what causes it, and what is the indication

What is SMA disease? The SMA disease (Spinal Muscular Atrophy), which has been frequently confronted recently, is the result of some cells in the spinal cord that are responsible for the movement of muscles and are unable to function. What is the indication of how the SMA disease is treated and how it is treated Spinal Muscular Atrophy (SMA) is a genetic disorder that has recently been spoken. SMA is seen in children. Significant progress has been made in the treatment of SMA disease. In the stem cell studies conducted by the University of California, achieving results as high as 95 percent is a great success. However, these experiments are currently being tested on whether or not cells will work on animals. Some of the cells in the spinal cord that are responsible for the muscle movements are sick and unable to perform their tasks. These cells are responsible for transmitting the movement command from the brain to the muscles. The muscles can not work because they can not get the movement order and they are weak. All arm and leg muscles, trunk, and some respiratory muscles are affected by this disease. MASTIC DISEASE AND SPECIFICATIONS Clinically, four types of SMA disease of different types and severities have been identified. Their characteristics are as follows according to their functional ability to move: SMA Type 1: The head control is not stable because the head is very weak.SMA Type 2: Head control. They can sit but can not go to sitting position from the lying position.SMA Type 3: They can stand and walk.SMA Type 4: It is the type seen in adults. Arm and legs have weakness. In general, these patients can walk.Spinal Muscular Atrophy is a hereditary disease, not contagious. In hereditary diseases, genes are disordered. Genes produce some proteins to function in cells. When the gene is defective, these proteins can not be produced, under-produced or over-produced. In this case, some damage may occur in the relevant cells. In SMA, the function of the anterior horn cell deteriorates and the muscles in the voluntary moving muscle are seen to dissolve with weakness. The gene defect causing the SMA disease is known. For this reason, diagnosis can be made during pregnancy if there is a disease in the family. It is also aimed at increasing the quality of life of the patient by providing certain treatments to the patient, while not being a specific treatment of this disease. However, two kinds of studies are being carried out in order to find the survivors of SMA disease with developing medical technology. One of them is genetic therapy. With this therapy, the causes of SMA disease are tried to be removed. The other form of therapy is cellular replacement therapy. In this way, dead cells or cells that are starting to die are being tried to be replaced by new ones. It is a great achievement that the results of stem cell studies made by the University of California, which is 95 percent higher. In previous studies, stem cells could be compared to spinal cord cells in only 20 percent purity. With this study, it was observed that injecting cells that did not meet the required functions into the spinal cord was not beneficial. The most important issue when injecting stem cells at the site to be applied is that the purity ratio is more than 95%. The professors of the University of California, which achieved this, are also considered to have received treatment for SMA. However, the effect of this treatment method on people is still being investigated. In the light of the results obtained, it is planned that the stem cells will be used to repair motor neuron damage in the spinal cord. It has been tried to work on cells, not on animals. The positive results are hope for SMA patients